The Ming Hsieh Institute

By bringing together faculty from USC's renowned programs in engineering, medicine, the sciences and pharmacy, the Ming Hsieh Institute cultivates an environment of creativity and collaboration. Read More »

Ming Hsieh developed a keen interest and skill in technology as a young child in northeastern China, learning from his electrical engineer father how to dismantle and reassemble everything from transistor radios to televisions.

Following in the footsteps of an uncle who earned a master's in mechanical engineering at USC, Hsieh enrolled at USC after two years of college at what is now the South China University of Technology in Guangzhou. He earned his B.S. in electrical engineering in 1983 and his M.S. in electrical engineering just one year later. Read More »

Ming Hsieh
June 5, 2018

Imaging Mass Cytometry to Profile Tumor Immune Microenvironment

Investigators: Akil Merchant M.D.; Parkash Gill M.D.; Peter Kuhn Ph.D.; Imran Siddiqi MD Ph.D.
Innovation: developing an imaging technique to study immune cells and understand their connection to tumors
Clinical significance: gain insights into immune response for patients being treated with immuno-oncology agents
June 5, 2018

Development of a Nano-Encapsulated Small Molecule Immunotherapeutic for Colon Cancer

Investigators: Nicos Petasis Ph.D.; Stan Louie Ph.D.; Heinz-Josef Lenz M.D.
Innovation: developing non-cytotoxic small molecules that cause tumor death through suppression of inflammation
Clinical significance: provides a new treatment for colon cancer and other inflammation-related cancers
June 5, 2018

Large-scale Isolation of Cytotoxic Extracellular Vesicles from Activated Natural Killer Cells for Immunotherapy of Cancer

Investigators: Noah Malmstadt Ph.D.; Robert Seeger M.D. M.S.; Muller Fabbri M.D. Ph.D.; Ambrose Jong Ph. D.; Alan Wayne M.D.
Innovation: develop a new, automated, large-scale device for purifying NK EVs and characterize their ability to kill human ALL and NB cell lines in vitro and cell lines and patient derived xenografts
Clinical significance: new approach to the treatment of cancer that may be effective against a wide array of malignancies in children and adults