Investigators: Richard Roberts, Ph.D.; Uttam Sinha, M.D.
Innovation: develop high-affinity peptides for targeted diagnosis and a pipeline for generating other reagents
Clinical significance: a robust, simple diagnostic test for early detection of head and neck cancers

Investigators: J. Andrew MacKay, Ph.D.; Peter Conti, M.D., Ph.D.
Innovation: developing a timepoint-independent pharmacokinetic modeling strategy
Clinical significance: improving personalized medicine by more accurately measuring the effects of a particular treatment on an individual patient

Investigators: Fabien Pinaud, Ph.D.; Mitchell Gross, M.D., Ph.D.; Charles McKenna, Ph.D.
Innovation: combining drugs that prevent bone loss with gold nanoparticles to treat metastatic bone cancer
Clinical significance: enhancing the chance of survival for patients with few current options