Controllable CAR T Cell Therapy by Focused Ultrasound for Pediatric Glioblastoma
July 18, 2023Development of Novel Antibody-Drug Conjugates for Metastatic Breast Cancer
July 18, 2023Innovative Ultrasound-Guided CAR-Macrophages for Safe and Effective Cancer Immunotherapy
The proposal aims to use focused ultrasound to confine the activation of genetically engineered macrophages within solid tumor tissues, thus avoiding non-specific attacks on normal cells. The research focuses on developing macrophages that can be activated with ultrasound for localized tumor eating or cytokine secretion to enhance cancer treatment. The research integrates engineering and medicine for clinical applications in cancer treatment.